Information for SPICA Directory Online initially was based on the book with the same name, published in the year 2001. This printed directory was created by the global network SPICE Group (Science Park and Innovation Center Experts) with support of almost all national and international associations of innovation centers who provided basic information. Of greatest importance was the support from IASP, International Science Park Association, NBIA, National Business Incubation Association, USA, and ADT, Association of German Technology and Business Innovation Centers.

In the year 2002 SPICE Group began implementing the Internet based version "SPICA Directory Online". Since then the system has been developed and responsibility for adding and updating the profiles of associations, incubators, and technoparks has been shifted gradually to the listed organizations themselves. The content management system allows listed institutions to update their information directly and keep it correct and actual. SPICE Group still is leading and coordinating all activities related with the directory, but cannot accept responsibility for the content of the individual profiles.